The Chief of Startup Success: Bridging Leadership and Operations for Excellence w/ Nikki Shakamuri
Nikki Shakamuri knows startups. As a two-time Chief of Staff, she’s helped early-stage companies go from scattered to streamlined. Her background in psychology, healthcare, and data gave her the foundation. But it’s her ability to build systems, manage energy, and stay human that makes her effective.
Key Takeaways
Structure beats chaos. Even basic systems make a huge difference in fast-moving teams.
You need the right CEO to grow with. Trust and mentorship matter.
Young professionals should try different roles before choosing a path. Be curious and open.
Notable Quotes
"Be extremely delusional in your 20s... whatever you think you can't do just say you're gonna do it like the biggest dream and just go for it."
"If they don't have the time they'll tell you or they'll delete the meeting or they'll slack you saying hey can you push it but if you don't put the meeting on they'll never know you need the help."
"I think there's a difference between hanging out with people who talk about work at dinner and hanging out with people that really fill your soul."
Real-World Applications
Learn Across Functions
Example: At Viraaal, Nikki asked questions across teams—creative, product, ops—so she could translate priorities across the company.Match With Mentors Who Invest
Example: Her first COO gave her 5–7 hours of coaching a week. That time shaped how she works—and now how she leads.Find Friends That Recharge You
Example: Nikki carves out time for non-work life—like Costco sample runs with close friends—to keep herself grounded and energized.
Nikki Shakamuri shows what it really takes to be a Chief of Staff at a startup. It’s not about doing everything—it’s about making sure the right things get done. She leads through listening, organizing, and asking the questions no one else will.
00:41 Journey into the Startup World
00:52 Transition from Healthcare to COS
02:07 Exploring Different Career Paths
05:39 The Importance of Mentorship
11:11 Working at Viral: A Startup Experience
12:36 The Role of a Chief of Staff in a Startup
16:11 Balancing Work and Personal Life
20:31 Advice for Aspiring Chiefs of Staff
30:38 Final Thoughts
About The Author
Emily Sander is an ICF-certified leadership coach with more than 15 years of experience in the business world and the author of Hacking Executive Leadership. She’s been featured in several print publications, online articles, and podcasts, including CEO Today Magazine, Leading to Fulfillment, and Leadership Powered by Common Sense.
Emily has a passion for helping business leaders reach their full potential. Go here to read her story from seasoned executive to knowledgeable coach. If you want to send Emily a quick message, then visit her contact page here.